{"id":586,"date":"2009-11-08T22:22:11","date_gmt":"2009-11-09T02:22:11","guid":{"rendered":"https:\/\/nltaylor.net\/sketchbook\/?p=586"},"modified":"2009-12-30T10:03:10","modified_gmt":"2009-12-30T14:03:10","slug":"taylor-dna-%e2%80%94-toward-a-historical-haplotype","status":"publish","type":"post","link":"https:\/\/nltaylor.net\/sketchbook\/archives\/586","title":{"rendered":"Taylor DNA \u2014 toward a historical haplotype"},"content":{"rendered":"<p>Well, apparently I don&#8217;t know how to scrape the inside of my cheeks properly, since the lab took extra long to culture my Y-chromosome DNA.  But I finally have a complete 37-marker Y-chromosome DNA test back, so now our Taylor family has three datapoints from which to triangulate a historical haplotype for our common ancestor, John<sup>3<\/sup> Taylor (d. 1741).  Here is the data from three test subjects, including me, in the tabular form published by <a href=\"http:\/\/www.familytreedna.com\/public\/taylorfamilygenes\/default.aspx?section=yresults\">familytreedna.com<\/a>:<\/p>\n<div align = 'center'><img decoding=\"async\" src=\"https:\/\/nltaylor.net\/sketchbook\/wp-content\/uploads\/2009\/11\/Taylor_YDNA-marked-37.png\"\/><\/div>\n<p>There are three boxes highlighted in blue, in which one value does not match the value for the others.  100194 differs from the others in the last locus, and 157892 differs from the others in two other loci (nos. 34 and 35 out of 37).  Each disagreement between values represents a mutation somewhere in the family tree, but where?  <!--more-->And where there is disagreement, which number is the &#8216;original&#8217; one, belonging to the common ancestor?  Having three test subjects with known places in the family tree permits a certain degree of confidence assessing the discrepancies.  The chart I put into <a href=\"https:\/\/nltaylor.net\/sketchbook\/archives\/553\">an earlier post<\/a> showed the descent of the three test subjects from two sons of John Taylor (d. 1741).  Here I include the same chart with the DNA test kit numbers below each of the subjects:<\/p>\n<div align = 'center'><img decoding=\"async\" src=\"https:\/\/nltaylor.net\/sketchbook\/wp-content\/uploads\/2009\/11\/Taylor-DNA2.gif\"\/><\/div>\n<p>This shows us that subject nos. 159898 and 100194 both descend from Harrison<sup>4<\/sup> Taylor (d. 1811), and subject 157892 descends from Harrison&#8217;s brother Simon<sup>4<\/sup> Taylor (d. 1786); both of these are sons of John<sup>3<\/sup> Taylor (d. 1741) who is the most recent common ancestor of all three subjects.<\/p>\n<p>In the one locus (the last one, locus 37) where 159898 and 157892 agree while 100194 does not, we can be certain that the mutation must have happened somewhere between 100194 and his ancestor Septimus<sup>5<\/sup> (son of Harrison<sup>4<\/sup>).  With the other two disagreements, where 100194 and 159898 differ from 157892, we don&#8217;t know which line has the mutation. We can assume that every value shared by 100194 and 159898 belonged to their common ancestor Harrison<sup>4<\/sup>.  Since 157892 has a different value, the mutation must lie somewhere between Harrison<sup>4<\/sup> and 157892.  There are nine possible individuals in whom each mutation might have occurred: Harrison<sup>4<\/sup> himself, his brother Simon<sup>4<\/sup>, or any of the seven other men down the line from Simon<sup>4<\/sup> to subject 157892. So there is a 1\/9 (or 11%) chance that it was actually Harrison<sup>4<\/sup> who had the mutation (and therefore the value borne by 157892 is the original); and an 8\/9 (or 89%) chance that 157892 bears the mutated value, the mutation having occurred somewhere between Simon and 157892 himself.  So in these two loci, 34 and 35, we aren&#8217;t yet certain which values were borne by the common ancestor, John<sup>3<\/sup> Taylor; and we won&#8217;t know until other subjects are tested, ideally who descend from an <i>earlier<\/i> common ancestor.  I have now contacted known descendants of John<sup>3<\/sup> Taylor&#8217;s brother George<sup>3<\/sup>, who hopefully can contribute DNA to this project!<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Well, apparently I don&#8217;t know how to scrape the inside of my cheeks properly, since the lab took extra long to culture my Y-chromosome DNA. But I finally have a complete 37-marker Y-chromosome DNA test back, so now our Taylor family has three datapoints from which to triangulate a historical haplotype for our common ancestor, [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[8,3],"tags":[],"class_list":["post-586","post","type-post","status-publish","format-standard","hentry","category-taylor-dna","category-us-genealogy"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Taylor DNA \u2014 toward a historical haplotype - a genealogist&#039;s sketchbook<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nltaylor.net\/sketchbook\/archives\/586\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Taylor DNA \u2014 toward a historical haplotype - a genealogist&#039;s sketchbook\" \/>\n<meta property=\"og:description\" content=\"Well, apparently I don&#8217;t know how to scrape the inside of my cheeks properly, since the lab took extra long to culture my Y-chromosome DNA. 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